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Scientists at deCODE genetics have demonstrated how measuring the levels of a large number of proteins in plasma at a population scale when combined with data on sequence diversity and RNA expression dramatically increases insights into human diseases and other phenotypes. The scientists have used levels of five thousand proteins in plasma targeted on a […]

The next phase in the company’s strategy towards 2023 is expected to affect around 1,000 positions in the global organization over the next two years. In 2020, LEO Pharma unveiled its strategy towards 2030. The first phase of this process – including the introduction of a new capital and governance structure – was recently completed. The next phase, announced now, […]

An international research team have mapped how the signalling molecules caused by exercise are releases by different organs in mice following exercise at different times of the day. Their atlas of exercise metabolism, published in the journal Cell Metabolism, may in the long term contribute to more effective exercise therapies that are timed to the […]

Cantargia has reported treatment of the first triple negative breast cancer (TNBC) patient with nadunolimab and chemotherapy in the phase Ib/II clinical trial TRIFOUR. This trial, performed in collaboration with the Spanish Breast Cancer Group, GEICAM, will evaluate nadunolimab in combination with gemcitabine and carboplatin in up to 113 patients. Initially, the trial will focus […]

Altos Labs has been launched as a new biotechnology company dedicated to unraveling the biology of cellular rejuvenation programming. Altos’ mission is to restore cell health and resilience to reverse disease, injury, and the disabilities that can occur throughout life, the company states. Based in the US and the UK The company launches with a […]

Spago Nanomedical has announced new results which show that the company’s candidate drug Tumorad significantly reduces tumor growth and prolongs survival in a preclinical model for colorectal cancer. Together with previously communicated clinical and preclinical results, the new results provide additional support for the company’s platform technology with nanoparticles for use in several different cancer […]

Masha Strømme, founder of PAACS Invest, shares her advice to aspiring life science entrepreneurs looking to succeed and make a difference for patients. A French-Canadian by birth, Masha Strømme prepared for a career in research, earning a doctorate in genetics and neuroscience thanks to a Rhodes Scholarship at the University of Oxford in the United […]

The European Commission has granted marketing authorization for Vyepti in the European Union for the prophylactic treatment of migraine in adults who have at least four migraine days per month. The approval follows the positive opinion on November 11th, 2021 from the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP). Vyepti […]

The company has contacted the US Food and Drug Administration and rescinded the October 22, 2021, letter requesting voluntary withdrawal of the NDA of Pepaxto (INN melphalan flufenamide, also called melflufen) in the US. Further review and analyses of the heterogenous Overall Survival data from the phase 3 OCEAN study and other relevant trials have […]

Anneli Hällgren has been appointed the new head of preclinical development, including regulatory safety studies. Hällgren has worked for the past ten years as a consultant in preclinical drug discovery and will now join the Aqilion team on a part-time basis. “I’m convinced that Anneli Hällgren’s expertise will be extremely valuable for Aqilion’s continued preparations […]